Chiefs vs. Chargers Prediction & Odds

Chiefs vs. Chargers, 11/20/22 NFL Betting Prediction, Odds & Trends

AFC West rivals clash in L.A. for Sunday Night Football in Week 11 when the Chargers host the Chiefs at 8:20 p.m. ET.

The road team has typically dominated this matchup from an ATS standpoint, but is 5.5 too many points to lay with the visiting Chiefs?

Game Matchup & Betting Odds

469 Kansas City Chiefs (-5.5) at 470 Los Angeles Chargers (+5.5); o/u 51.5

8:20 p.m. ET, Sunday, November 20, 2022

SoFi Stadium, Los Angeles, CA

Chiefs vs. Chargers Public Betting Information

Our NFL Public Betting Information page indicates that 51% of public bettors are currently backing the Chargers when it comes to the spread. This information is subject to change throughout the day, however, so be sure to check the link so you’re receiving the most up-to-date public betting data.

Kansas City Chiefs DFS Spin

Patrick Mahomes completed 26 of 35 passes for 331 yards with four touchdowns and one interception in the Chiefs' 27-17 win over the Jaguars on Sunday. He also rushed seven times for 39 yards and fumbled once but recovered. Mahomes worked through the early exit of JuJu Smith-Schuster (concussion) without much issue, pivoting to targeting Travis Kelce, Marquez Valdes-Scantling, versatile running back Jerick McKinnon and newcomer Kadarius Toney with plenty of success. Mahomes connected with Toney (six yards), Valdes-Scantling (18 yards), Noah Gray (13 yards) and Kelce (seven yards) for his scoring tosses, and he'll head into a Week 11 divisional road clash against the Chargers next Sunday night having thrown multiple touchdown passes in five of his last six games.

Los Angeles Chargers DFS Spin

Justin Herbert completed 21 of 35 passes for 196 yards, a touchdown and an interception in Sunday's 22-16 loss to the 49ers. He also ran the ball five times for 22 yards. Herbert and the Chargers put together a brilliant opening drive that culminated in a wide-open touchdown to DeAndre Carter, but the offense was unable to score another touchdown from that point forward as the 49ers never allowed a big play. The superstar quarterback briefly was forced to leave the game to end the second quarter after taking a crushing hit, but after passing concussion protocols Herbert was allowed to return to the game. Up next is a pivotal divisional matchup against the Chiefs, who allowed Herbert to rack up 334 passing yards in a Week 2 Chargers loss.

Chiefs vs. Chargers Betting Trends

Chiefs are 1-4-1 ATS in their last 6 meetings

Over is 7-1 in Chiefs last 8 road games

Over is 4-1 in Chiefs last 5 vs. AFC West

Over is 6-2 in Chargers last 8 home games

Chiefs vs. Chargers Prediction:

The road team is 16-4-1 against the spread in their last 21 meetings between these two teams, while the Chiefs have covered in eight of their last nine games in L.A/San Diego. Kansas City is also 9-4 against the spread in its last 13 games after accumulating more than 350 total yards in its previous game and is 15-6-1 at the betting window in its last 22 road games when facing an opponent with a winning home record. Speaking of that opponent, the Chargers are just 3-10 against the spread in their last 13 games played in the month of November and are 21-44-1 against the number in their last 66 home games.


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