Rams vs. 49ers Total Prediction

Rams vs. 49ers, 10/3/22 Over/Under Betting Prediction & Odds

NFC West rivals clash in San Francisco for Monday Night Football as the 49ers host the Rams at 8:15 p.m. ET. Given the offensive struggles for the 49ers, is the under the wise play or will these division foes get over the 42.5-point total?

Game Matchup & Betting Odds

279 Los Angeles Rams (+1.5) at 280 San Francisco 49ers (-1.5); o/u 42.5

8:15 p.m. ET, Monday, October 3, 2022

Levi’s Stadium, Santa Clara, CA

Rams vs. 49ers Public Betting Information

Our NFL Public Betting Information page indicates that 63% of public bettors are currently backing the Rams when it comes to the spread. This information is subject to change throughout the day, however, so be sure to check the link so you’re receiving the most up-to-date public betting data.

Los Angeles Rams DFS Spin

Allen Robinson caught 2-of-5 targets for 23 yards in the Rams' Week 3 win over the Cardinals. Robinson's five targets were good enough for a 20% share and second on the team to Cooper Kupp's six, but Robinson dropped a would-be touchdown at the goal line on a quick slant, and he and Matthew Stafford couldn't hook up on a couple other red-zone looks. It's clear the Rams are trying to get Robinson involved, but the connection with Stafford isn't yet crisp. Robinson has seven catches for 88 yards and one touchdown through three games. He'll be a back-end WR3 for Week 4 against the Niners.

San Francisco 49ers DFS Spin

Speaking Monday, 49ers HC Kyle Shanahan indicated that LT Trent Williams (ankle) could be out for 4-6 weeks.  Shanahan was ambiguous on Williams' timeline, telling reporters that it would be difficult to know until the swelling went down. Shanahan did confirm that Williams suffered a high ankle sprain. Even if Williams' injury isn't as bad as feared Shanahan indicated that he still expects him to miss "some time." It's an unfortunate development for one of the best tackles in football. Jimmy Garoppolo may have less time to throw in the coming weeks.

Rams vs. 49ers Betting Trends

Rams are 0-5 ATS in their last 5 meetings

Rams are 2-5 ATS in their last 7 meetings in San Francisco

Road team is 5-2 ATS in their last 7 meetings

Rams vs. 49ers Prediction:

The under is 7-2 in the last nine meetings between these two teams when the game is in San Francisco and has cashed in four of their last five meetings overall. The under is also 4-1 in the Rams’ last five games overall, is 12-3-1 in their last 16 games played in the month of October and is 9-3-1 in their last 13 games when facing an opponent with a losing record. On the other side, the under is 5-0 in the 49ers’ last five conference games, is 5-0 in their last five games coming off a loss and is 4-1 in their last five home games.

NFL WEEK 4 PREDICTION: RAMS/49ERS UNDER 42.5

Recent NFL Discussions

NFL Predictions & Picks

Thumbnail Saints vs. Buccaneers Prediction & Odds NFC South rivals clash on Monday Night Football when the Bucs host the Saints at 8:15 p.m. ET. Will Tom Brady and the Bucs cash as 3.5-point home favorites or...
Thumbnail Saints vs. Buccaneers Total Prediction The under has been highly profitable in previous meetings between the Saints and Bucs, who will meet on Monday Night Football at 8:15...
Thumbnail Colts vs. Cowboys SNF Prediction & Odds The Sunday Night Football matchup between the Colts and Cowboys figures to be a blowout in Dallas, but does the total have some value? Kickoff for this...
Thumbnail Dolphins vs. 49ers Prediction & Odds Two teams fighting for playoff positioning in their respective conferences will clash in San Clara, CA on Sunday when the 49ers host the Dolphins at 4:05 p.m....
Thumbnail Chiefs vs. Bengals Prediction & Odds One of the best matchups in Week 13 will take place in Cincinnati on Sunday when the Bengals host the Chiefs at 4:25 p.m. ET.

NFL Headlines