Notre Dame vs. USC Prediction & Odds

Notre Dame vs. USC, 11/26/22 CFB Betting Odds, Prediction & Trends

Notre Dame has struggled to cover in previous trips to Southern Cal but are the Fighting Irish the sharp side of Saturday night’s 7:30 p.m. ET matchup?

Game Matchup & Betting Odds

199 Notre Dame Fighting vs. 200 USC Trojans (-4.5); o/u 64.5

7:30 p.m. ET, Saturday, November 26, 2022

United Airlines Field at Los Angeles Memorial Coliseum

Notre Dame vs. USC Public Betting Information

As of this writing, our CFB Public Betting page shows that 54% of bets are on USC. That said, this page is updated frequently so make sure that you click on the link provided so that you’re getting the most updated information.

Notre Dame Fighting Irish Game Notes

Drew Pyne completed 13-of-25 pass attempts for 156 yards and one touchdown as a snowstorm and the score curtailed the passing game in the Irish 44-0 win over Boston College on Nov. 19. Notre Dame was already ahead 23-0 with nine minutes remaining in the first half. Pyne's lone touchdown came in the first quarter. The junior could be in for a much bigger passing day on Saturday, Nov. 26 when the Irish travel to Southern California, who is near the bottom in the FBS against the passing, allowing 258 yards per game.

USC Trojans Game Notes

Caleb Williams completed 32 of 43 passes for 470 yards, two touchdowns and one interception during Saturday's 48-45 victory versus UCLA. He also had eight rushes for 33 yards with one touchdown. Saturday's game was a high-flying back-and-forth battle, and every time the Bruins scored, the Trojans were able to answer. Although USC's defense can be credited for saving the day with a slew of turnovers, Williams delivered in racking up the score when necessary, With two ranked opponents on the horizon, the Trojans have a legit shot at making the playoff, and if Williams can post similar numbers over the next two weeks, the Heisman trophy could be his.

Notre Dame vs. USC Betting Trends

Over is 5-0 in Fighting Irish last 5 games overall

Over is 5-0 in Fighting Irish last 5 non-conference games

Over is 4-1 in Fighting Irish last 5 road games

Over is 5-0 in Trojans last 5 games overall

Notre Dame vs. USC Miss Betting Prediction

The Fighting Irish are just 2-7 against the spread in their last nine games in Southern Cal, while the favorite is 7-2 against the number in the last nine meetings between these two teams and the home side is 7-1 at the betting window in the last nine USC-ND matchups. The Trojans are also 5-2 against the spread in their last seven home games, are 5-1 against the number in their last six games versus a team with a winning record and are 6-2 ATS in their last eight home games versus a team with a winning road record.


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