Michigan State vs. Duke Prediction

Michigan State vs. Duke, 3/20/22 March Madness Betting Predictions

After outlasting Davidson in their opening round matchup, will 7 seed Michigan State put up a fight against 2 seed Duke from the West Region on Sunday evening when the two teams meet at 5:15 p.m. ET? The Blue Devils are currently 6.5-point favorites to knock off Sparty.

Game Snapshot

817 Michigan State Spartans (+6.5) vs. 818 Duke Blue Devils (-6.5); o/u 144.5

5:15p.m. ET, Bon Secours Wellness Arena, Greenville, SC

TV: CBS

March Madness Betting Prediction

The underdog is a perfect 5-0 against the spread in the last five meetings between these two teams, while the Spartans are 5-0 against the number in their last five games overall. Michigan State is also 5-0 against the spread in its last five neutral site games, is 4-1 against the number in its last five neutral site games as an underdog and has cashed in four of its last five games when facing an opponent with a winning percentage above .600.

On the other side, the Blue Devils have failed to cover in each of their last five games overall, are now winless at the betting window in their last seven NCAA Tournament games when listed as a favorite and are 0-5 against the number in their last five games overall after failing to cover against CS Fullerton in their opening round matchup. Duke is just 3-7 against the spread in its last 10 games coming off a win as well.

MARCH MADNESS BETTING PREDICTION: MICHIGAN STATE SPARTANS +6.5

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