Astros vs. Red Sox Game 5 Prediction

Astros vs. Red Sox, 10/20/21 Game 5 ALCS Playoffs Betting Predictions

The ALCS is now all tied at two games apiece following the Astros’ come-from-behind victory over the Red Sox on Tuesday night. Who has the edge in Game 5 this evening when Framber Valdez opposes Chris Sale in the pitching matchup at 5:08 p.m. ET?

Game Snapshot

915 Houston Astros (+105) at 916 Boston Red Sox (-125); o/u 9.5

5:08 p.m. ET, Wednesday, October 20, 2021

Fenway Park, Boston, MA

TV: FS1

Houston Astros DFS Notes

Framber Valdez will start for the Astros in Game 5 of the ALCS on Wednesday versus the Red Sox. Valdez was said to be available in relief in Game 4 on Tuesday, but the Astros were able to steer away from him as they earned a 9-2 victory in Boston to knot the best-of-seven American League Championship Series at two games apiece. The 27-year-old left-hander lasted just 2 2/3 innings in his ALCS Game 1 start last Friday in Houston. He'll be matched up against Chris Sale in Game 5 at Fenway Park.

Boston Red Sox DFS Notes

Chris Sale will get the start for the Red Sox in Game 5 of the ALCS on Wednesday against the Astros. Sale hasn't made it very deep into his two postseason starts thus far, but he's probably the best option for manager Alex Cora as the Red Sox look to jump back ahead in the best-of-seven series, which is currently tied 2-2 after Houston's come-from-behind win in Game 4 on Tuesday night at Fenway Park. Framber Valdez will be on the bump first Wednesday for the visiting 'Stros.

Astros vs. Red Sox Game 5 ALCS Betting Prediction

The over is now 6-0 in the last six meetings between these two teams and is 4-0 in the last four meetings at Fenway Park. The over is also 6-0 in the Astros’ last six games as an underdog, is 7-0 in their last seven playoff games and is 4-0 in their last four road games. On the other side, the over is 7-0 in the Red Sox’ last seven games overall, is 5-0 in their last five games when favored and is 7-0 in their last seven games when facing an opponent with a winning record.

2021 NLCS GAME 5 MLB PLAYOFFS BETTING PREDICTION: ASTROS/RED SOX OVER 9.5

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